It's been a big year for the long undruggable target. The first inhibitor — Lumakras sotorasib from Amgen Inc. — reached the market in May under the accelerated approval pathway for non-small cell lung cancer (NSCLC), and Amgen and Mirati both revealed strong proof of concept in colorectal cancer at this month’s European Society for Clinical Oncology (ESMO) Congress.
Shanghai-based GenFleet has been developing GFH925 as a treatment for non-small cell lung cancer and other solid tumors.
Chinese pharma companies Innovent and GenFleet have entered into an exclusive licensing agreement for developing and commercializing GenFleet’s GFH925, the company’s lead KRAS G12C candidate in the China, Hong Kong, Macau and Taiwan markets.
GenFleet Therapeutics raised $58 million in series B funding to bankroll clinical trials of its pipeline, including a small molecule for liver cancer.
For the last decade or so, many of the more eye-catching Chinese biotech startups share two defining attributes
With eight preclinical candidates and an experienced management team, immunology company GenFleet Therapeutics Co. Ltd. (Shanghai, China) raised RMB120 million ($17.4 million) in an untranched series A round to bring its first therapy into clinic next year.
